3TNH
CDK9/cyclin T in complex with CAN508
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 9 | polymer | 331 | 38054.1 | 1 | UniProt (P50750) Pfam (PF00069) In PDB | Homo sapiens (human) | C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE |
| 2 | B | Cyclin-T1 | polymer | 259 | 30139.5 | 1 | UniProt (O60563) Pfam (PF00134) Pfam (PF21797) In PDB | Homo sapiens (human) | CycT1, Cyclin-T |
| 3 | A | 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL | non-polymer | 218.2 | 1 | Chemie (F18) |
Sequence modifications
A: 2 - 330 (UniProt: P50750)
B: 1 - 259 (UniProt: O60563)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Pro 1 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Leu 241 | Phe 241 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68193.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 218.2 | |
| All* | Total formula weight | 68411.8 |
