3TKS
Crystal structure of full-length human peroxiredoxin 4 in three different redox states
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxiredoxin-4 | polymer | 246 | 28027.6 | 2 | UniProt (Q13162) Pfam (PF00578) Pfam (PF10417) | Homo sapiens (human) | Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372 |
| 2 | C, D (C, D) | Peroxiredoxin-4 | polymer | 246 | 28043.6 | 2 | UniProt (Q13162) Pfam (PF00578) Pfam (PF10417) | Homo sapiens (human) | Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372 |
| 3 | E (E) | Peroxiredoxin-4 | polymer | 246 | 28011.6 | 1 | UniProt (Q13162) Pfam (PF00578) Pfam (PF10417) | Homo sapiens (human) | Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372 |
| 4 | F, G, H (A, C, D) | PEROXIDE ION | non-polymer | 32.0 | 3 | Chemie (PER) | |||
| 5 | I, J, K, L, M (A, B, C, D, E) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 234 (UniProt: Q13162)
C, D: 1 - 234 (UniProt: Q13162)
E: 1 - 234 (UniProt: Q13162)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | expression tag |
| Arg -10 | - | expression tag |
| Gly -9 | - | expression tag |
| Ser -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 140154.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 96.0 | |
| All* | Total formula weight | 140250.0 |
