3TKR

Crystal structure of full-length human peroxiredoxin 4 with T118E mutation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, I, G, C, F...	Peroxiredoxin-4	polymer	246	28039.6	10	UniProt (Q13162) Pfam (PF00578) Pfam (PF10417) In PDB	Homo sapiens (human)	Antioxidant enzyme AOE372, AOE37-2, Peroxiredoxin IV, Prx-IV, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxide reductase A0372
2		water	water		18.0	2135	Chemie (HOH)

Sequence modifications

A, I, G, C, F, D, B, H, E, J: 1 - 234 (UniProt: Q13162)

PDB	External Database	Details
Met -11	-	expression tag
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Glu 118	Thr 155	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	280396.2
All*	Total formula weight	280396.2

*Water molecules are not included.