3THQ

Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with 6-amino-UMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotidine 5'-phosphate decarboxylase	polymer	247	26795.8	2	UniProt (O26232) Pfam (PF00215)	Methanothermobacter thermautotrophicus (Methanococcus thermolithotrophicus)	OMP decarboxylase, OMPDCase, OMPdecase
2	C, D (A, B)	6-AMINOURIDINE 5'-MONOPHOSPHATE	non-polymer		339.2	2	Chemie (NUP)
3	E (B)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	1	Chemie (EPE)
4	F, G (A, B)	water	water		18.0	214	Chemie (HOH)

Sequence modifications

A, B: 1 - 228 (UniProt: O26232)

PDB	External Database	Details
Pro 101	Arg 101	conflict
Ile 227	Asn 227	conflict
Glu 229	-	expression tag
Asp 230	-	expression tag
Pro 231	-	expression tag
Ala 232	-	expression tag
Ala 233	-	expression tag
Asn 234	-	expression tag
Lys 235	-	expression tag
Ala 236	-	expression tag
Arg 237	-	expression tag
Lys 238	-	expression tag
Glu 239	-	expression tag
Ala 240	-	expression tag
Glu 241	-	expression tag
Leu 242	-	expression tag
Ala 243	-	expression tag
Ala 244	-	expression tag
Ala 245	-	expression tag
Thr 246	-	expression tag
Ala 247	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53591.7
Non-Polymers*	Number of molecules	3
	Total formula weight	916.7
All*	Total formula weight	54508.4

*Water molecules are not included.