3TGU
Cytochrome bc1 complex from chicken with pfvs-designed moa inhibitor bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, K (A, N) | Mitochondrial ubiquinol-cytochrome-c reductase complex core protein i | polymer | 446 | 49503.8 | 2 | UniProt (D0VX31) | Gallus gallus (bantam chickens) | UQCRC1 |
| 2 | B, L (B, O) | Mitochondrial ubiquinol-cytochrome-c reductase complex core protein 2 | polymer | 441 | 46683.8 | 2 | UniProt (D0VX29) | Gallus gallus (bantam chickens) | UQCRC2 |
| 3 | C, M (C, P) | Cytochrome b | polymer | 380 | 42651.0 | 2 | UniProt (P18946) Pfam (PF00033) Pfam (PF00032) | Gallus gallus (bantam chickens) | Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit |
| 4 | D, N (D, Q) | Mitochondrial cytochrome c1, heme protein | polymer | 241 | 26973.7 | 2 | UniProt (D0VX26) | Gallus gallus (bantam chickens) | |
| 5 | E, O (E, R) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 196 | 21506.2 | 2 | UniProt (Q5ZLR5) Pfam (PF02921) Pfam (PF00355) | Gallus gallus (bantam chickens) | Complex III subunit 5, Rieske iron-sulfur protein, RISP, Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 6 | F, P (F, S) | Mitochondrial ubiquinol-cytochrome c reductase 14 kda protein | polymer | 110 | 13394.4 | 2 | UniProt (D0VX30) | Gallus gallus (bantam chickens) | UQCRB |
| 7 | G, Q (G, T) | Mitochondrial ubiquinol-cytochrome c reductase ubiquinone-binding protein qp-c | polymer | 81 | 9498.7 | 2 | UniProt (D0VX32) | Gallus gallus (bantam chickens) | UQCRQ |
| 8 | H, R (H, U) | Mitochondrial ubiquinol-cytochrome c reductase 11 kda protein, complex iii subunit viii | polymer | 77 | 9057.1 | 2 | UniProt (D0VX28) | Gallus gallus (bantam chickens) | UQCRH, HINGE PROTEIN |
| 9 | I, S (I, V) | Cytochrome b-c1 complex subunit Rieske, mitochondrial | polymer | 76 | 7721.1 | 2 | UniProt (Q5ZLR5) Pfam (PF09165) | Gallus gallus (bantam chickens) | Complex III subunit 5, Rieske iron-sulfur protein, RISP, Ubiquinol-cytochrome c reductase iron-sulfur subunit |
| 10 | J, T (J, W) | Mitochondrial ubiquinol-cytochrome c reductase 7.2 kda protein | polymer | 61 | 7006.0 | 2 | UniProt (D0VX27) | Gallus gallus (bantam chickens) | UQCR10 |
| 11 | JA, U (N, A) | UNKNOWN LIGAND | non-polymer | 2 | Chemie (UNL) | ||||
| 12 | LA, MA, V, W (P, C) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 13 | OA, X (P, C) | methyl (2E)-3-methoxy-2-[2-({[6-methyl-3-(trifluoromethyl)quinoxalin-2-yl]oxy}methyl)phenyl]prop-2-enoate | non-polymer | 432.4 | 2 | Chemie (WF3) PubChem (60172031) | |||
| 14 | PA, Y (P, C) | Coenzyme Q10, (2Z,6E,10Z,14E,18E,22E,26Z)-isomer | non-polymer | 863.3 | 2 | Chemie (UQ) PubChem (17572160) PubChem (45266508) PubChem (1156) PubChem (5281915) PubChem (5366029) PubChem (5354031) PubChem (6473741) PubChem (5926222) PubChem (97038292) PubChem (97038293) PubChem (6857782) PubChem (9811994) PubChem (12303768) PubChem (12303769) PubChem (124919119) PubChem (124919120) PubChem (131954658) PubChem (137350098) | |||
| 15 | IA, QA, UA, Z (G, P, Q, C) | CARDIOLIPIN | non-polymer | 1464.0 | 4 | Chemie (CDL) PubChem (17753886) PubChem (5287898) | |||
| 16 | AA, BA, HA, KA, RA... (C, E, N, P, R) | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine | non-polymer | 744.0 | 6 | Chemie (PEE) PubChem (108229) PubChem (44891344) PubChem (54095275) PubChem (14238554) PubChem (5909904) PubChem (9546757) PubChem (6437392) PubChem (99655478) PubChem (99655479) PubChem (9546744) PubChem (138113035) PubChem (171729549) | |||
| 17 | CA, SA (C, P) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 18 | DA, TA (D, Q) | HEME C | non-polymer | 618.5 | 2 | Chemie (HEC) | |||
| 19 | EA, FA, NA, VA, WA (D, P, Q) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 5 | Chemie (BOG) | |||
| 20 | GA, XA (E, R) | FE2/S2 (INORGANIC) CLUSTER | non-polymer | 175.8 | 2 | Chemie (FES) | |||
| 21 | AB, BB, CB, ZA (E, P, R, C) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence modifications
C, P: 2 - 380 (UniProt: P18946)
I, V: 2 - 8 (UniProt: Q5ZLR5)
I, V: 50 - 78 (UniProt: Q5ZLR5)
| PDB | External Database | Details |
|---|---|---|
| Fme 1 | - | initiating methionine |
I, V: 50 - 78 (UniProt: Q5ZLR5)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 20 |
| Total formula weight | 467991.7 | |
| Non-Polymers* | Number of molecules | 31 |
| Total formula weight | 18612.5 | |
| All* | Total formula weight | 486604.2 |
