3TG3

Crystal structure of the MAPK binding domain of MKP7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Dual specificity protein phosphatase 16	polymer	142	15989.4	4	UniProt (Q9BY84) Pfam (PF00581) In PDB	Homo sapiens (human)	Mitogen-activated protein kinase phosphatase 7, MAP kinase phosphatase 7, MKP-7
2	C, D	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
3		water	water		18.0	86	Chemie (HOH)

Sequence modifications

A, B, C, D: 5 - 138 (UniProt: Q9BY84)

PDB	External Database	Details
Leu 139	-	expression tag
Glu 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag
His 144	-	expression tag
His 145	-	expression tag
His 146	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	63957.6
Non-Polymers*	Number of molecules	2
	Total formula weight	124.1
All*	Total formula weight	64081.7

*Water molecules are not included.