3TFP
Crystal Structure of Dehydrosqualene Synthase (CrtM) from S. aureus Complexed with BPH-1162
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dehydrosqualene synthase | polymer | 293 | 34787.5 | 1 | UniProt (A9JQL9) Pfam (PF00494) | Staphylococcus aureus | 4,4'-diapophytoene synthase, DAP synthase, Diapophytoene synthase |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | 2-({2-chloro-6-[(2,4-dichlorophenyl)sulfanyl]benzyl}carbamoyl)benzoic acid | non-polymer | 466.8 | 1 | Chemie (03L) | |||
| 4 | E (A) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 1 - 287 (UniProt: A9JQL9)
| PDB | External Database | Details |
|---|---|---|
| Ala -5 | - | expression tag |
| Ala -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34787.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 515.4 | |
| All* | Total formula weight | 35302.9 |
