3TDB
Human Pin1 bound to trans peptidomimetic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | polymer | 158 | 17609.6 | 1 | UniProt (Q13526) Pfam (PF00397) Pfam (PF00639) | Homo sapiens (human) | Peptidyl-prolyl cis-trans isomerase Pin1, PPIase Pin1, Rotamase Pin1 |
| 2 | B (A) | N-[(1E,2R)-1-[(2R)-2-{[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}cyclopentylidene]-3-(phosphonooxy)propan-2-yl]-L-phenylalaninamide | non-polymer | 567.6 | 1 | Chemie (3TB) | |||
| 3 | C (A) | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL | non-polymer | 354.4 | 1 | Chemie (PE4) | |||
| 4 | D (A) | water | water | 18.0 | 64 | Chemie (HOH) |
Sequence modifications
A: 6 - 163 (UniProt: Q13526)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Arg 14 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17609.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 922.0 | |
| All* | Total formula weight | 18531.6 |
