3T9V
CNQX bound to a reduced double cysteine mutant (A452C/S652C) of the ligand binding domain of GluA2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glutamate receptor 2 | polymer | 258 | 28883.5 | 2 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) Pfam (PF00497) In PDB | Rattus norvegicus (rat) | GluA2, GluR2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2 |
| 2 | A, B | 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile | non-polymer | 230.1 | 2 | Chemie (CNI) | |||
| 3 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B: 4 - 117 (UniProt: P19491)
A, B: 120 - 261 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Cys 63 | Ala 473 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Cys 140 | Ser 673 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57766.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 721.9 | |
| All* | Total formula weight | 58488.8 |
