Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CNI A 400 |
| Chain | Residue |
| A | GLU13 |
| A | MET196 |
| A | TYR220 |
| A | HOH422 |
| A | HOH518 |
| A | TYR61 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | THR174 |
| A | GLU193 |
| A | THR195 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CNI B 400 |
| Chain | Residue |
| B | GLU13 |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | THR174 |
| B | THR195 |
| B | MET196 |
| B | TYR220 |
| B | HOH308 |
| B | HOH479 |
| B | HOH509 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | HIS23 |
| A | HOH421 |
| B | HOH492 |
| B | HOH526 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 2 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 3 |
| Chain | Residue |
| A | ASP139 |
| B | HIS23 |
| B | GLU24 |
| B | HOH360 |
| B | HOH461 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 262 |
| Chain | Residue |
| B | GLU42 |
| B | HIS46 |
| B | GLN244 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLU193 | |
| B | TYR61 | |
| B | ARG96 | |
| B | GLU193 | |
| A | TYR61 | |
| A | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | PRO89 | |
| A | PRO89 | |
| Chain | Residue | Details |
| B | SER142 | |
| B | THR143 | |
| A | THR143 | |
| B | THR91 | |
| A | THR91 | |
| A | SER142 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| B | ARG64 | |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
