3T9C
Crystal structure of the catalytic domain of human diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) in complex with AMPPNP and inositol hexakisphosphate (IP6)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Inositol Pyrophosphate Kinase | polymer | 330 | 37568.9 | 1 | UniProt (O43314) Pfam (PF18086) In PDB | Homo sapiens (human) | |
| 2 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | A | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
A: 41 - 366 (UniProt: O43314)
| PDB | External Database | Details |
|---|---|---|
| Gly 37 | - | expression tag |
| Ser 38 | - | expression tag |
| Phe 39 | - | expression tag |
| Thr 40 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37568.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1263.5 | |
| All* | Total formula weight | 38832.3 |
