3T6A

Structure of the C-terminal domain of BCAR3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Breast cancer anti-estrogen resistance protein 3	polymer	333	38009.8	4	UniProt (O75815) Pfam (PF00617) In PDB	Homo sapiens (human)	Novel SH2-containing protein 2, SH2 domain-containing protein 3B
2	A, B	(20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL	non-polymer		424.6	2	Chemie (POG)
3	D	UNKNOWN ATOM OR ION	non-polymer			8	Chemie (UNX)
4		water	water		18.0	373	Chemie (HOH)

Sequence modifications

A, B, C, D: 502 - 825 (UniProt: O75815)

PDB	External Database	Details
Met 501	-	initiating methionine
Leu 536	Met 536	engineered mutation
Leu 826	-	expression tag
Glu 827	-	expression tag
His 828	-	expression tag
His 829	-	expression tag
His 830	-	expression tag
His 831	-	expression tag
His 832	-	expression tag
His 833	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	152039.3
Non-Polymers*	Number of molecules	10
	Total formula weight	849.1
All*	Total formula weight	152888.4

*Water molecules are not included.