3T6A
Structure of the C-terminal domain of BCAR3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0007264 | biological_process | small GTPase-mediated signal transduction |
| B | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| B | 0007264 | biological_process | small GTPase-mediated signal transduction |
| C | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| C | 0007264 | biological_process | small GTPase-mediated signal transduction |
| D | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| D | 0007264 | biological_process | small GTPase-mediated signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE POG A 834 |
| Chain | Residue |
| A | SER697 |
| C | ARG748 |
| C | GLU752 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE POG B 834 |
| Chain | Residue |
| B | ALA745 |
| B | THR746 |
| B | HOH835 |
| D | SER697 |
| D | ASN742 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1080 |
| Details | Domain: {"description":"Ras-GEF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00168","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Region: {"description":"Mediates the interaction with BCAR1/p130CAS","evidences":[{"source":"PubMed","id":"22081014","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Required for interaction with NEDD9","evidences":[{"source":"UniProtKB","id":"Q9QZK2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
