3T2N

Human hepsin protease in complex with the Fab fragment of an inhibitory antibody

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Serine protease hepsin	polymer	372	40491.8	2	UniProt (P05981) Pfam (PF09272) Pfam (PF00089) In PDB	Homo sapiens (human)	Transmembrane protease serine 1, Serine protease hepsin non-catalytic chain, Serine protease hepsin catalytic chain
2	H, I	Antibody, Fab fragment, Heavy Chain	polymer	225	23967.9	2		Homo sapiens (human)
3	L, M	Antibody, Fab fragment, Light Chain	polymer	215	22881.4	2		Homo sapiens (human)
4		water	water		18.0	315	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	174682.2
All*	Total formula weight	174682.2

*Water molecules are not included.