3SWR
Structure of human DNMT1 (601-1600) in complex with Sinefungin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA (cytosine-5)-methyltransferase 1 | polymer | 1002 | 113665.6 | 1 | UniProt (P26358) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) | Homo sapiens (human) | Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, DNA MTase HsaI, M.HsaI, MCMT |
| 2 | B (A) | SINEFUNGIN | non-polymer | 381.4 | 1 | Chemie (SFG) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D, E (A) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | AA, BA, CA, DA, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 25 | Chemie (EDO) | |||
| 6 | EA, FA, GA, HA (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 7 | IA (A) | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A: 601 - 1600 (UniProt: P26358)
| PDB | External Database | Details |
|---|---|---|
| His 599 | - | expression tag |
| Met 600 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 113665.6 | |
| Non-Polymers* | Number of molecules | 33 |
| Total formula weight | 2681.3 | |
| All* | Total formula weight | 116346.9 |
