3SW2
X-ray crystal structure of human FXA in complex with 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Coagulation factor X | polymer | 94 | 10213.3 | 1 | UniProt (P00742) Pfam (PF00008) Pfam (PF14670) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 2 | B (B) | Coagulation factor X | polymer | 238 | 26871.6 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (human) | Stuart factor, Stuart-Prower factor |
| 3 | C (B) | 6-chloro-N-((3S)-2-oxo-1-(2-oxo-2-((5S)-8-oxo-5,6-dihydro-1H-1,5-methanopyrido[1,2-a][1,5]diazocin-3(2H,4H,8H)-yl)ethyl)piperidin-3-yl)naphthalene-2-sulfonamide | non-polymer | 569.1 | 1 | Chemie (FI1) | |||
| 4 | D (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 5 | E (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | G, H (A, B) | water | water | 18.0 | 83 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37085.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 724.2 | |
| All* | Total formula weight | 37809.2 |
