3SRK
A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Pyruvate kinase | polymer | 499 | 54467.9 | 2 | UniProt (Q27686) Pfam (PF00224) Pfam (PF02887) | Leishmania mexicana | PK |
| 2 | C, G (A, B) | 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE | non-polymer | 183.2 | 2 | Chemie (LSA) | |||
| 3 | D, E, H, I (A, B) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | F (A) | pyrene-1,3,6,8-tetrasulfonic acid | non-polymer | 522.5 | 1 | Chemie (PTK) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 137 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 108935.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1045.3 | |
| All* | Total formula weight | 109981.1 |
