3SQZ

Crystal structure of HMG_CoA synthase complexed with CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Putative hydroxymethylglutaryl-CoA synthase	polymer	425	47219.7	1	UniProt (Q8DUI5) Pfam (PF08540)	Streptococcus mutans
2	B, C (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	D (A)	COENZYME A	non-polymer		767.5	1	Chemie (COA)
4	E (A)	water	water		18.0	351	Chemie (HOH)

Sequence modifications

A: 1 - 391 (UniProt: Q8DUI5)

PDB	External Database	Details
Met -33	-	expression tag
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Csd 111	Cys 111	microheterogeneity

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47219.7
Non-Polymers*	Number of molecules	3
	Total formula weight	951.7
All*	Total formula weight	48171.5

*Water molecules are not included.