3SQD

Crystal structure of human PTIP BRCT5/6-gamma H2AX complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PAX-interacting protein 1	polymer	219	25147.2	2	UniProt (Q6ZW49) Pfam (PF00533) Pfam (PF16589)	Homo sapiens (human)	ptip, PAX transactivation activation domain-interacting protein
2	C, D (C, D)	Histone H2A.x	polymer	10	1235.2	2	UniProt (P16104)	Homo sapiens	H2AX, H2a/x
3	E, F, G, H (A, B, C, D)	water	water		18.0	273	Chemie (HOH)

Sequence modifications

A, B: 860 - 1069 (UniProt: Q6ZW49)

PDB	External Database	Details
Met 851	-	expression tag
Gly 852	-	expression tag
His 853	-	expression tag
His 854	-	expression tag
His 855	-	expression tag
His 856	-	expression tag
His 857	-	expression tag
His 858	-	expression tag
Met 859	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	52764.8
All*	Total formula weight	52764.8

*Water molecules are not included.