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3SPH

Inward rectifier potassium channel Kir2.2 I223L mutant in complex with PIP2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Inward-rectifier K+ channel Kir2.2polymer34339361.71UniProt (D2YW45)
Pfam (PF01007)
Pfam (PF17655)
UniProt (by SIFTS) (F1NHE9)
Gallus gallus (chicken)inward rectifier potassium channel 2.2
2B, C, D, E
(A)
POTASSIUM IONnon-polymer39.14Chemie (K)
3F
(A)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.61Chemie (PIO)
Sequence modifications
A: 36 - 378 (UniProt: D2YW45)
PDBExternal DatabaseDetails
Leu 223Ile 188engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39361.7
Non-Polymers*Number of molecules5
Total formula weight903.0
All*Total formula weight40264.7
*Water molecules are not included.

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PDB entries from 2025-07-23

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