3SP8
Crystal structure of NK2 in complex with fractionated Heparin DP10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Hepatocyte growth factor alpha chain | polymer | 264 | 30910.1 | 2 | UniProt (P14210) Pfam (PF00024) Pfam (PF00051) In PDB | Homo sapiens (human) | Hepatopoeitin-A, Scatter factor, SF |
2 | A, B | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 4 | Chemie (MRD) | |||
3 | A, B | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 4 | Chemie (MES) | |||
4 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
5 | A, B | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
6 | water | water | 18.0 | 359 | Chemie (HOH) |
Sequence modifications
A, B: 28 - 288 (UniProt: P14210)
PDB | External Database | Details |
---|---|---|
Gly 26 | - | expression tag |
Ser 27 | - | expression tag |
Asp 146 | Gly 146 | engineered mutation |
Ser 214 | Cys 214 | engineered mutation |
Lys 284 | Ala 284 | conflict |
Lys 289 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 61820.2 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 2332.4 | |
All* | Total formula weight | 64152.7 |