3SP7
Crystal Structure of Bcl-xL bound to BM903
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bcl-2-like protein 1 | polymer | 172 | 19676.6 | 1 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (human) | Bcl-xL, Bcl2-L-1, Apoptosis regulator Bcl-X |
| 2 | A | 5-(4-chlorophenyl)-4-{3-[4-(4-{[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrophenyl)sulfonyl]amino}phenyl)piperazin-1-yl]phenyl}-1,2-dimethyl-1H-pyrrole-3-carboxylic acid | non-polymer | 908.5 | 1 | Chemie (03B) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | A | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 5 | water | water | 18.0 | 175 | Chemie (HOH) |
Sequence modifications
A: 1 - 84 (UniProt: Q07817)
A: 85 - 209 (UniProt: Q07817)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Glu -1 | - | expression tag |
| Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19676.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1347.3 | |
| All* | Total formula weight | 21023.9 |
