3SP5
Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 14-3-3 protein sigma | polymer | 235 | 26505.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (human) | Epithelial cell marker protein 1, Stratifin |
2 | P | TASK-3 peptide | polymer | 6 | 857.0 | 1 | UniProt (by SIFTS) (Q9NPC2) In PDB | Homo sapiens | |
3 | A | Cotylenol | non-polymer | 350.5 | 1 | Chemie (CX7) | |||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
5 | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDB | External Database | Details |
---|---|---|
Ala -3 | - | expression tag |
Met -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Val 38 | Cys 38 | engineered mutation |
His 166 | Asn 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 27362.8 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 399.1 | |
All* | Total formula weight | 27761.9 |