3SNP

Crystal structure analysis of iron regulatory protein 1 in complex with ferritin H IRE RNA

Replaces:  2IPY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Cytoplasmic aconitate hydratase	polymer	908	100776.7	2	UniProt (Q01059) Pfam (PF00330) Pfam (PF00694)	Oryctolagus cuniculus (rabbit)	Iron regulatory protein 1, IRP1, Aconitase, Citrate hydro-lyase, Ferritin repressor protein, Iron-responsive element-binding protein 1, IRE-BP 1
2	C, D (C, D)	ferritin H IRE RNA	polymer	30	9568.7	2
3	E, F, G, H (A, B, C, D)	water	water		18.0	557	Chemie (HOH)

Sequence modifications

A, B: 2 - 889 (UniProt: Q01059)

PDB	External Database	Details
Met -18	-	expression tag
Gly -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ala -10	-	expression tag
Asp -9	-	expression tag
Asp -8	-	expression tag
Asp -7	-	expression tag
Asp -6	-	expression tag
Lys -5	-	expression tag
Asp -4	-	expression tag
Gly -3	-	expression tag
Val -2	-	expression tag
Asp -1	-	expression tag
Lys 0	-	expression tag
Leu 1	-	expression tag
Pro 283	Leu 283	SEE REMARK 999
Ser 437	Cys 437	engineered mutation
Ser 503	Cys 503	engineered mutation
Phe 874	Leu 874	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	220690.8
All*	Total formula weight	220690.8

*Water molecules are not included.