3SMI
Human poly(ADP-ribose) polymerase 14 (Parp14/Artd8) - catalytic domain in complex with a quinazoline inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Poly [ADP-ribose] polymerase 14 | polymer | 193 | 22118.6 | 2 | UniProt (Q460N5) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-14, B aggressive lymphoma protein 2 |
| 2 | A, B | 2-{[(3-amino-1H-1,2,4-triazol-5-yl)sulfanyl]methyl}-8-methylquinazolin-4(3H)-one | non-polymer | 288.3 | 2 | Chemie (QDR) | |||
| 3 | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A, B: 1530 - 1720 (UniProt: Q460N5)
| PDB | External Database | Details |
|---|---|---|
| Ser 1528 | - | expression tag |
| Met 1529 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44237.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 576.7 | |
| All* | Total formula weight | 44813.8 |
