3SL4
Crystal structure of the catalytic domain of PDE4D2 with compound 10D
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | polymer | 361 | 41523.9 | 4 | UniProt (Q08499) Pfam (PF00233) | Homo sapiens (human) | DPDE3, PDE43 |
| 2 | BA, CA, E, F, KB... (B, A, D, C) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | AA, AC, BB, CB, CC... (A, D, C, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 51 | Chemie (EDO) | |||
| 4 | AB, FA, FC, I, QB... (C, B, D, A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 8 | Chemie (DMS) | |||
| 5 | BC, JB, N, UB, YB (D, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 6 | GB, GC, QA, V (C, D, B, A) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 7 | HB, HC, RA, X (C, D, B, A) | ethenyl 6-(ethenylcarbamoyl)-2-[(phenylacetyl)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate | non-polymer | 411.5 | 4 | Chemie (JN4) | |||
| 8 | EA, YA (B, C) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 9 | IC, JC, KC, LC (A, B, C, D) | water | water | 18.0 | 467 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 166095.5 | |
| Non-Polymers* | Number of molecules | 82 |
| Total formula weight | 7346.8 | |
| All* | Total formula weight | 173442.3 |
