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3SL3

Crystal structure of the apo form of the catalytic domain of PDE4D2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
cAMP-specific 3',5'-cyclic phosphodiesterase 4Dpolymer36141523.94UniProt (Q08499)
Pfam (PF00233)
Homo sapiens (human)DPDE3, PDE43
2AA, AB, BA, BB, CA...
(B, C, D, A)
1,2-ETHANEDIOLnon-polymer62.160Chemie (EDO)
3PA, R, RB, TB
(B, A, D)
DI(HYDROXYETHYL)ETHERnon-polymer106.14Chemie (PEG)
4AC, DB, EB, HA, IA...
(D, C, B, A)
ZINC IONnon-polymer65.48Chemie (ZN)
5BC, FB, JA, U
(D, C, B, A)
PHOSPHATE IONnon-polymer95.04Chemie (PO4)
6IB, MA, NA, NB, VA
(D, B, C)
DIMETHYL SULFOXIDEnon-polymer78.15Chemie (DMS)
7UA
(C)
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACIDnon-polymer238.31Chemie (EPE)
8IC, JC, KC, LC
(A, B, C, D)
waterwater18.0412Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight166095.5
Non-Polymers*Number of molecules82
Total formula weight5680.7
All*Total formula weight171776.2
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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