3SL3
Crystal structure of the apo form of the catalytic domain of PDE4D2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| C | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| C | 0007165 | biological_process | signal transduction |
| C | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| D | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| D | 0007165 | biological_process | signal transduction |
| D | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1 |
| Chain | Residue |
| A | LYS262 |
| A | ASP266 |
| A | HOH550 |
| A | HOH588 |
| B | HOH531 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| D | DMS6 |
| D | GLU182 |
| A | EDO20 |
| A | LEU188 |
| A | LYS255 |
| A | GLN256 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 3 |
| Chain | Residue |
| A | EDO9 |
| A | ASN115 |
| A | ARG116 |
| A | GLU150 |
| A | ASP151 |
| A | TYR153 |
| A | ASN162 |
| A | HOH545 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 4 |
| Chain | Residue |
| A | PHE238 |
| A | ARG257 |
| A | HOH590 |
| A | HOH602 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 5 |
| Chain | Residue |
| A | EDO12 |
| A | ASP156 |
| A | ALA158 |
| A | PRO205 |
| A | ARG342 |
| A | ARG346 |
| A | HOH599 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | EDO7 |
| A | PHE135 |
| A | GLN256 |
| A | HOH511 |
| D | DMS6 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 7 |
| Chain | Residue |
| A | EDO6 |
| A | THR134 |
| A | LYS136 |
| D | EDO9 |
| D | PRO179 |
| D | ASP391 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 8 |
| Chain | Residue |
| A | GLN250 |
| A | ASN251 |
| A | HOH548 |
| A | HOH577 |
| D | HOH556 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 9 |
| Chain | Residue |
| A | EDO3 |
| A | ASP151 |
| A | TYR153 |
| A | HIS154 |
| A | ALA155 |
| A | HOH545 |
| C | ASP156 |
| C | HOH483 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 10 |
| Chain | Residue |
| A | THR178 |
| A | ASP391 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 11 |
| Chain | Residue |
| A | PO416 |
| A | GLU230 |
| A | THR271 |
| A | ASP272 |
| A | MET273 |
| A | HOH567 |
| A | HOH574 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 12 |
| Chain | Residue |
| A | EDO5 |
| A | HIS154 |
| A | ASP156 |
| A | VAL157 |
| A | PRO205 |
| C | HOH474 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG A 13 |
| Chain | Residue |
| A | LEU132 |
| A | LYS136 |
| A | ILE137 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 14 |
| Chain | Residue |
| A | PO416 |
| A | ASP201 |
| A | HOH528 |
| A | HOH529 |
| A | HOH573 |
| A | HOH574 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 15 |
| Chain | Residue |
| A | PO416 |
| A | HIS164 |
| A | HIS200 |
| A | ASP201 |
| A | ASP318 |
| A | HOH573 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 16 |
| Chain | Residue |
| A | EDO11 |
| A | ZN14 |
| A | ZN15 |
| A | HIS160 |
| A | HIS164 |
| A | ASP201 |
| A | ASP318 |
| A | HOH509 |
| A | HOH530 |
| A | HOH573 |
| site_id | BC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO A 17 |
| Chain | Residue |
| A | LYS275 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 18 |
| Chain | Residue |
| A | PHE340 |
| A | GLN343 |
| A | HIS204 |
| A | GLY206 |
| A | VAL207 |
| A | GLU339 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 19 |
| Chain | Residue |
| A | THR148 |
| A | HIS152 |
| A | GLU243 |
| A | HOH555 |
| C | SER217 |
| C | ARG350 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 20 |
| Chain | Residue |
| A | EDO2 |
| A | THR186 |
| A | LEU188 |
| A | SER259 |
| A | MET263 |
| A | HOH580 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 21 |
| Chain | Residue |
| A | LYS239 |
| A | GLN242 |
| A | GLU243 |
| C | EDO18 |
| C | ASN216 |
| C | SER217 |
| C | GLU218 |
| D | GLN242 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1 |
| Chain | Residue |
| B | DMS15 |
| B | GLN210 |
| B | HOH511 |
| B | HOH531 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 2 |
| Chain | Residue |
| B | ALA183 |
| B | VAL184 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 3 |
| Chain | Residue |
| B | THR289 |
| B | LYS291 |
| B | LEU298 |
| B | LEU299 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 4 |
| Chain | Residue |
| B | ASN115 |
| B | ALA155 |
| B | ASN161 |
| B | ASN162 |
| B | ARG335 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 5 |
| Chain | Residue |
| B | LEU175 |
| B | THR178 |
| B | TRP384 |
| B | ASP391 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 6 |
| Chain | Residue |
| B | ASP374 |
| B | HIS378 |
| B | HOH541 |
| site_id | DC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 7 |
| Chain | Residue |
| B | DMS14 |
| B | HIS204 |
| B | GLY206 |
| B | VAL207 |
| B | GLU339 |
| B | PHE340 |
| B | GLN343 |
| B | HOH517 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 8 |
| Chain | Residue |
| B | PO410 |
| B | ASP201 |
| B | HOH524 |
| B | HOH525 |
| B | HOH526 |
| B | HOH569 |
| site_id | DC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 9 |
| Chain | Residue |
| B | PO410 |
| B | HIS164 |
| B | HIS200 |
| B | ASP201 |
| B | ASP318 |
| B | HOH569 |
| site_id | DC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 B 10 |
| Chain | Residue |
| B | ZN8 |
| B | ZN9 |
| B | HIS160 |
| B | HIS164 |
| B | ASP201 |
| B | ASP318 |
| B | HOH567 |
| B | HOH569 |
| B | HOH574 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 11 |
| Chain | Residue |
| B | GLU218 |
| D | HIS152 |
| D | LYS239 |
| D | HOH594 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 12 |
| Chain | Residue |
| B | ILE354 |
| B | SER355 |
| B | MET357 |
| B | CYS358 |
| B | ASP359 |
| B | ASN362 |
| site_id | DC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 13 |
| Chain | Residue |
| B | ASP334 |
| B | MET337 |
| B | GLU338 |
| B | PHE341 |
| site_id | DC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS B 14 |
| Chain | Residue |
| B | EDO7 |
| B | SER208 |
| B | GLN343 |
| B | PRO356 |
| B | CYS358 |
| B | HOH565 |
| site_id | DC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 15 |
| Chain | Residue |
| B | EDO1 |
| B | GLN210 |
| B | SER274 |
| B | HOH577 |
| B | HOH584 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 16 |
| Chain | Residue |
| B | THR186 |
| B | ASP187 |
| B | HOH582 |
| site_id | EC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PEG B 17 |
| Chain | Residue |
| B | HIS152 |
| B | GLU243 |
| B | HOH519 |
| D | THR215 |
| D | SER217 |
| D | GLU218 |
| D | LEU219 |
| D | ARG350 |
| site_id | EC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 1 |
| Chain | Residue |
| A | ARG350 |
| C | HIS152 |
| C | GLU243 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 7 |
| Chain | Residue |
| A | GLU244 |
| C | ASN214 |
| C | ARG350 |
| C | MET352 |
| C | HOH506 |
| D | LYS254 |
| site_id | EC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 2 |
| Chain | Residue |
| A | GLU218 |
| C | TYR223 |
| C | HIS232 |
| C | ALA235 |
| C | HOH463 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 3 |
| Chain | Residue |
| A | ASP156 |
| C | EDO13 |
| C | GLU150 |
| C | ASP151 |
| C | TYR153 |
| C | ASN162 |
| site_id | EC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE C 4 |
| Chain | Residue |
| C | HIS105 |
| C | VAL106 |
| C | PHE107 |
| C | ARG108 |
| C | GLU111 |
| C | GLN327 |
| C | LEU328 |
| C | GLN331 |
| site_id | EC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE DMS C 5 |
| Chain | Residue |
| C | ARG257 |
| C | ARG261 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 6 |
| Chain | Residue |
| C | LYS262 |
| C | ASP266 |
| D | ASN224 |
| site_id | FC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 12 |
| Chain | Residue |
| C | LYS275 |
| C | HOH465 |
| site_id | FC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 8 |
| Chain | Residue |
| B | HIS389 |
| B | PRO390 |
| C | THR134 |
| C | PHE135 |
| C | LYS136 |
| C | ASN251 |
| C | GLN256 |
| site_id | FC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO C 9 |
| Chain | Residue |
| C | ASP203 |
| C | LEU219 |
| site_id | FC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 10 |
| Chain | Residue |
| C | ASP156 |
| C | VAL157 |
| C | PRO205 |
| C | ARG342 |
| C | ARG346 |
| C | HOH468 |
| C | HOH502 |
| site_id | FC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 11 |
| Chain | Residue |
| C | HIS160 |
| C | HIS204 |
| C | GLY206 |
| C | VAL207 |
| C | GLU339 |
| C | PHE340 |
| C | GLN343 |
| site_id | FC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 13 |
| Chain | Residue |
| C | EDO3 |
| C | ASN115 |
| C | ALA155 |
| C | ASN161 |
| C | ASN162 |
| C | ILE163 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C 14 |
| Chain | Residue |
| C | PO416 |
| C | ASP201 |
| C | HOH456 |
| C | HOH457 |
| C | HOH458 |
| C | HOH459 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C 15 |
| Chain | Residue |
| C | PO416 |
| C | HIS164 |
| C | HIS200 |
| C | ASP201 |
| C | ASP318 |
| C | HOH458 |
| site_id | FC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 C 16 |
| Chain | Residue |
| C | ZN14 |
| C | ZN15 |
| C | HOH58 |
| C | HIS160 |
| C | HIS164 |
| C | ASP201 |
| C | ASP318 |
| C | HOH458 |
| site_id | GC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 18 |
| Chain | Residue |
| A | EDO21 |
| A | GLU243 |
| A | HOH555 |
| C | GLU218 |
| site_id | GC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 4 |
| Chain | Residue |
| D | ASP266 |
| D | GLN311 |
| site_id | GC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE DMS D 6 |
| Chain | Residue |
| A | EDO2 |
| A | EDO6 |
| D | SER177 |
| D | PRO179 |
| D | GLU182 |
| D | HOH553 |
| site_id | GC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 1 |
| Chain | Residue |
| B | SER217 |
| B | HOH502 |
| D | EDO23 |
| D | THR148 |
| D | HIS152 |
| D | GLU243 |
| site_id | GC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO D 9 |
| Chain | Residue |
| A | EDO7 |
| A | THR134 |
| A | PHE135 |
| A | ASN251 |
| A | GLN256 |
| D | PRO179 |
| D | ASP391 |
| site_id | GC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 2 |
| Chain | Residue |
| D | EDO5 |
| D | LEU175 |
| D | THR178 |
| D | VAL388 |
| D | ASP391 |
| D | HOH541 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 3 |
| Chain | Residue |
| D | LEU181 |
| D | ALA183 |
| D | VAL184 |
| D | PHE185 |
| D | HOH553 |
| site_id | GC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS D 25 |
| Chain | Residue |
| D | GLU150 |
| D | ASP151 |
| D | TYR153 |
| D | ASN162 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 5 |
| Chain | Residue |
| D | EDO2 |
| D | ASN100 |
| D | LYS101 |
| D | TRP102 |
| D | HOH550 |
| site_id | HC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 27 |
| Chain | Residue |
| D | ASN100 |
| D | GLU128 |
| D | HIS173 |
| D | SER177 |
| site_id | HC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO D 7 |
| Chain | Residue |
| D | HIS123 |
| site_id | HC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG D 8 |
| Chain | Residue |
| C | ASP225 |
| C | HOH461 |
| D | GLN258 |
| D | LYS262 |
| D | ASP266 |
| site_id | HC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 10 |
| Chain | Residue |
| D | ASN302 |
| D | TYR303 |
| D | SER304 |
| site_id | HC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG D 11 |
| Chain | Residue |
| D | THR186 |
| D | LEU188 |
| D | GLU189 |
| D | SER259 |
| D | MET263 |
| D | HOH523 |
| site_id | HC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 12 |
| Chain | Residue |
| D | ASP247 |
| D | PHE249 |
| D | ARG257 |
| site_id | HC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 13 |
| Chain | Residue |
| D | ASP156 |
| D | VAL157 |
| D | ALA158 |
| D | GLU338 |
| D | GLU339 |
| D | HOH605 |
| site_id | HC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 14 |
| Chain | Residue |
| D | PRO325 |
| D | LEU326 |
| D | GLN327 |
| D | HOH582 |
| site_id | HC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 15 |
| Chain | Residue |
| D | GLU244 |
| D | ASN245 |
| D | SER294 |
| D | GLY296 |
| D | HOH520 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 16 |
| Chain | Residue |
| D | THR134 |
| D | LYS136 |
| D | ASN251 |
| D | GLN256 |
| site_id | IC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 17 |
| Chain | Residue |
| D | PO419 |
| D | ASP201 |
| D | HOH535 |
| D | HOH536 |
| D | HOH537 |
| site_id | IC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 18 |
| Chain | Residue |
| D | PO419 |
| D | HIS164 |
| D | HIS200 |
| D | ASP201 |
| D | ASP318 |
| site_id | IC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 D 19 |
| Chain | Residue |
| D | ZN17 |
| D | ZN18 |
| D | HIS160 |
| D | HIS164 |
| D | ASP201 |
| D | ASP318 |
| D | HOH574 |
| site_id | IC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 20 |
| Chain | Residue |
| D | MET286 |
| D | THR289 |
| D | ASP305 |
| site_id | IC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 21 |
| Chain | Residue |
| D | GLN127 |
| D | HOH507 |
| site_id | IC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO D 22 |
| Chain | Residue |
| D | ASP98 |
| D | LYS101 |
| D | TRP102 |
| site_id | IC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 23 |
| Chain | Residue |
| B | THR215 |
| B | ARG350 |
| D | EDO1 |
| D | THR148 |
| D | GLU243 |
| D | GLU244 |
| D | CYS246 |
| D | HOH554 |
| site_id | IC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 24 |
| Chain | Residue |
| D | ASN321 |
| D | THR333 |
| D | ILE336 |
| D | GLN369 |
| D | HOH529 |
| site_id | JC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO D 26 |
| Chain | Residue |
| D | ASP266 |
| D | GLN311 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDVdHpGvsNqF |
| Chain | Residue | Details |
| A | HIS200-PHE211 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:Q07343 |
| Chain | Residue | Details |
| A | HIS160 | |
| B | HIS160 | |
| C | HIS160 | |
| D | HIS160 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14609333, ECO:0000269|PubMed:15260978, ECO:0007744|PDB:1PTW, ECO:0007744|PDB:1TB7 |
| Chain | Residue | Details |
| A | HIS160 | |
| D | HIS160 | |
| D | ASN321 | |
| D | GLN369 | |
| A | ASN321 | |
| A | GLN369 | |
| B | HIS160 | |
| B | ASN321 | |
| B | GLN369 | |
| C | HIS160 | |
| C | ASN321 | |
| C | GLN369 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14609333, ECO:0000269|PubMed:15260978, ECO:0000269|PubMed:15576036, ECO:0000269|PubMed:17582435, ECO:0007744|PDB:1PTW, ECO:0007744|PDB:1TB7, ECO:0007744|PDB:1TBB, ECO:0007744|PDB:1XOM, ECO:0007744|PDB:1XON, ECO:0007744|PDB:1XOQ, ECO:0007744|PDB:2PW3 |
| Chain | Residue | Details |
| A | HIS164 | |
| B | HIS164 | |
| C | HIS164 | |
| D | HIS164 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14609333, ECO:0000269|PubMed:15260978, ECO:0000269|PubMed:15576036, ECO:0000269|PubMed:17582435, ECO:0007744|PDB:1PTW, ECO:0007744|PDB:1TB7, ECO:0007744|PDB:1TBB, ECO:0007744|PDB:1XOM, ECO:0007744|PDB:1XON, ECO:0007744|PDB:1XOQ, ECO:0007744|PDB:1XOR, ECO:0007744|PDB:2PW3 |
| Chain | Residue | Details |
| A | HIS200 | |
| A | ASP318 | |
| B | HIS200 | |
| B | ASP318 | |
| C | HIS200 | |
| C | ASP318 | |
| D | HIS200 | |
| D | ASP318 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14609333, ECO:0007744|PDB:1PTW |
| Chain | Residue | Details |
| A | ASP201 | |
| A | PHE372 | |
| B | ASP201 | |
| B | PHE372 | |
| C | ASP201 | |
| C | PHE372 | |
| D | ASP201 | |
| D | PHE372 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) |
| Chain | Residue | Details |
| A | LYS85 | |
| B | LYS85 | |
| C | LYS85 | |
| D | LYS85 |
