3SIQ

Crystal Structure of autoinhibited dIAP1-BIR1 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Apoptosis 1 inhibitor	polymer	136	15996.9	6	UniProt (Q24306) Pfam (PF00653)	Drosophila melanogaster (Fruit fly)	E3 ubiquitin-protein ligase th, Inhibitor of apoptosis 1, dIAP1, Protein thread
2	G, H, I, J, K... (A, B, C, D, E...)	ZINC ION	non-polymer		65.4	6	Chemie (ZN)
3	M, N, O (A, B, F)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 135 (UniProt: Q24306)

PDB	External Database	Details
-	Ala 6	deletion
-	Asp 7	deletion
-	Leu 8	deletion
-	Pro 9	deletion
-	Ser 10	deletion
-	Tyr 11	deletion
-	Gly 12	deletion
Ser 89	Cys 89	engineered mutation
Leu 136	-	expression tag
Glu 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag
His 141	-	expression tag
His 142	-	expression tag
His 143	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95981.5
Non-Polymers*	Number of molecules	6
	Total formula weight	392.5
All*	Total formula weight	96374.0

*Water molecules are not included.