3SI0
Structure of glycosylated human glutaminyl cyclase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Glutaminyl-peptide cyclotransferase | polymer | 330 | 37873.7 | 1 | UniProt (Q16769) Pfam (PF04389) In PDB | Homo sapiens (human) | Glutaminyl cyclase, QC, sQC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 150 | Chemie (HOH) |
Sequence modifications
A: 38 - 361 (UniProt: Q16769)
| PDB | External Database | Details |
|---|---|---|
| His 32 | - | expression tag |
| His 33 | - | expression tag |
| His 34 | - | expression tag |
| His 35 | - | expression tag |
| His 36 | - | expression tag |
| His 37 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37873.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 169.9 | |
| All* | Total formula weight | 38468.1 |
