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3SHV

Crystal structure of human MCPH1 tandem BRCT domains-gamma H2AX complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Microcephalinpolymer20622872.62UniProt (Q8NEM0)Homo sapiens (human)
2C, D
(C, D)
Histone H2A.xpolymer101235.22UniProt (P16104)Homo sapiens
3E, F, G, H
(A, B, C, D)
waterwater18.0182Chemie (HOH)
Sequence modifications
A, B: 639 - 835 (UniProt: Q8NEM0)
PDBExternal DatabaseDetails
Met 630-expression tag
Gly 631-expression tag
His 632-expression tag
His 633-expression tag
His 634-expression tag
His 635-expression tag
His 636-expression tag
His 637-expression tag
Met 638-expression tag
Ala 761Val 761SEE REMARK 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight48215.7
All*Total formula weight48215.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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