3SHV
Crystal structure of human MCPH1 tandem BRCT domains-gamma H2AX complex
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by ATM, ATR and PRKDC => ECO:0000269|PubMed:10477747, ECO:0000269|PubMed:10734083, ECO:0000269|PubMed:10959836, ECO:0000269|PubMed:11673449, ECO:0000269|PubMed:12419185, ECO:0000269|PubMed:12607005, ECO:0000269|PubMed:12660252, ECO:0000269|PubMed:12697768, ECO:0000269|PubMed:14627815, ECO:0000269|PubMed:15059890, ECO:0000269|PubMed:15489221, ECO:0000269|PubMed:15613478, ECO:0000269|PubMed:17709392, ECO:0000269|PubMed:22154951, ECO:0000269|PubMed:9488723, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692 |
| Chain | Residue | Details |
| C | SEP139 | |
| D | SEP139 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine; by WSTF => ECO:0000269|PubMed:19092802, ECO:0000269|PubMed:19234442 |
| Chain | Residue | Details |
| C | TYR142 | |
| D | TYR142 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| C | LYS134 | |
| D | LYS134 |
