3SGZ
High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl)sulfanyl]-1, 2, 3-thiadiazole.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Hydroxyacid oxidase 2 | polymer | 352 | 39059.0 | 3 | UniProt (Q07523) Pfam (PF01070) | Rattus norvegicus (rat) | HAOX2, (S)-2-hydroxy-acid oxidase, peroxisomal, Long chain alpha-hydroxy acid oxidase, Long-chain L-2-hydroxy acid oxidase |
| 2 | D, F, H (A, B, C) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 3 | Chemie (FMN) | |||
| 3 | E, G, I (A, B, C) | 5-[(4-methylphenyl)sulfanyl]-1,2,3-thiadiazole-4-carboxylic acid | non-polymer | 252.3 | 3 | Chemie (HO6) | |||
| 4 | J, K, L (A, B, C) | water | water | 18.0 | 1104 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 352 (UniProt: Q07523)
| PDB | External Database | Details |
|---|---|---|
| Lys 180 | Leu 181 | conflict |
| Ala 181 | Lys 182 | conflict |
| Ala 182 | Asp 183 | conflict |
| Leu 198 | Ser 199 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 117177.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2126.0 | |
| All* | Total formula weight | 119302.9 |
