3SGW

Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ribose 5-phosphate isomerase	polymer	184	19709.5	1	UniProt (P0CL19) Pfam (PF02502) In PDB	Coccidioides immitis (Valley fever fungus)
2	A	MALONIC ACID	non-polymer		104.1	1	Chemie (MLA)
3	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
5		water	water		18.0	168	Chemie (HOH)

Sequence modifications

A: 1 - 163 (UniProt: P0CL19)

PDB	External Database	Details
Met -20	-	initiating methionine
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19709.5
Non-Polymers*	Number of molecules	5
	Total formula weight	299.1
All*	Total formula weight	20008.6

*Water molecules are not included.