3SGW

Crystal structure of ribose-5-phosphate isomerase B RpiB from Coccidioides immitis semi-covalently bound to malonic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016853	molecular_function	isomerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE MLA A 164

Chain	Residue
A	ASP16
A	ASN110
A	CL168
A	HOH308
A	HOH312
A	HOH313
A	TYR53
A	CYS76
A	GLY77
A	THR78
A	GLY79
A	LEU80
A	GLY81
A	VAL82

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 165

Chain	Residue
A	ARG71
A	ASP111
A	ALA112
A	HOH183
A	HOH238

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 166

Chain	Residue
A	LYS88
A	LYS88
A	PHE159
A	PHE159
A	HOH199
A	HOH199

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 167

Chain	Residue
A	ASP99
A	ASP99
A	THR100
A	THR100

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 168

Chain	Residue
A	ARG120
A	MLA164
A	HOH311
A	HOH313

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21995815, ECO:0007744|PDB:3SGW

Chain	Residue	Details
A	CYS76

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:21995815, ECO:0007744|PDB:3SGW

Chain	Residue	Details
A	ASP16
A	GLY77

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P9WKD7

Chain	Residue	Details
A	ASN110
A	ARG120
A	LYS148

---