3SFG
crystal structure of murine norovirus RNA dependent RNA polymerase in complex with 2thiouridine(2TU)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | RNA polymerase | polymer | 517 | 58519.5 | 3 | UniProt (Q80J95) | Murine norovirus 1 | |
| 2 | AA, D, RA (B, A, C) | 1-(beta-D-ribofuranosyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one | non-polymer | 260.3 | 3 | Chemie (2TU) PubChem (3036443) PubChem (176590136) PubChem (26501901) PubChem (26501902) PubChem (29164112) PubChem (22792081) PubChem (40850837) PubChem (46500308) PubChem (712748) PubChem (1262955) PubChem (57175628) PubChem (57375564) PubChem (5175675) PubChem (89449757) PubChem (89495312) PubChem (12517389) PubChem (124301945) PubChem (124508368) PubChem (171699345) | |||
| 3 | AB, BA, BB, CA, CB... (C, B, A) | SULFATE ION | non-polymer | 96.1 | 28 | Chemie (SO4) | |||
| 4 | DB, EB, FB, GB, HB... (C, B, A) | GLYCEROL | non-polymer | 92.1 | 25 | Chemie (GOL) PubChem (753) | |||
| 5 | JB, QA, Z (C, B, A) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) PubChem (888) | |||
| 6 | KB, LB, MB (A, B, C) | water | water | 18.0 | 543 | Chemie (HOH) |
Sequence modifications
A, B, C: 4 - 509 (UniProt: Q80J95)
| PDB | External Database | Details |
|---|---|---|
| Ala 510 | - | expression tag |
| Ala 511 | - | expression tag |
| Ala 512 | - | expression tag |
| Leu 513 | - | expression tag |
| Glu 514 | - | expression tag |
| His 515 | - | expression tag |
| His 516 | - | expression tag |
| His 517 | - | expression tag |
| His 518 | - | expression tag |
| His 519 | - | expression tag |
| His 520 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 175558.6 | |
| Non-Polymers* | Number of molecules | 59 |
| Total formula weight | 5845.8 | |
| All* | Total formula weight | 181404.4 |
