3SEC

Crystal structure of Methanothermobacter thermautotrophicus orotidine 5'-monophosphate decarboxylase complexed with pyrazofurin monophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Orotidine 5'-phosphate decarboxylase	polymer	247	26795.8	1	UniProt (O26232) Pfam (PF00215) In PDB	Methanothermobacter thermautotrophicus (Methanococcus thermolithotrophicus)	OMP decarboxylase, OMPDCase, OMPdecase
2	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	A	(1S)-1,4-anhydro-1-(5-carbamoyl-4-hydroxy-1H-pyrazol-3-yl)-5-O-phosphono-D-ribitol	non-polymer		339.2	1	Chemie (PFU)
4		water	water		18.0	146	Chemie (HOH)

Sequence modifications

A: 1 - 228 (UniProt: O26232)

PDB	External Database	Details
Pro 101	Arg 101	conflict
Ile 227	Asn 227	conflict
Glu 229	-	expression tag
Asp 230	-	expression tag
Pro 231	-	expression tag
Ala 232	-	expression tag
Ala 233	-	expression tag
Asn 234	-	expression tag
Lys 235	-	expression tag
Ala 236	-	expression tag
Arg 237	-	expression tag
Lys 238	-	expression tag
Glu 239	-	expression tag
Ala 240	-	expression tag
Glu 241	-	expression tag
Leu 242	-	expression tag
Ala 243	-	expression tag
Ala 244	-	expression tag
Ala 245	-	expression tag
Thr 246	-	expression tag
Ala 247	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	26795.8
Non-Polymers*	Number of molecules	2
	Total formula weight	431.3
All*	Total formula weight	27227.1

*Water molecules are not included.