3SAO
The Siderocalin Ex-FABP functions through dual ligand specificities
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Extracellular fatty acid-binding protein | polymer | 160 | 18198.8 | 2 | UniProt (P21760) Pfam (PF00061) | Gallus gallus (chicken) | Ex-FABP, Protein Ch21, Quiescence-specific protein, p20K |
| 2 | C, D (A, B) | (2R)-2-hydroxy-3-(phosphonooxy)propyl tetradecanoate | non-polymer | 382.4 | 2 | Chemie (NKN) | |||
| 3 | E (B) | 2,3-DIHYDROXY-BENZOIC ACID | non-polymer | 154.1 | 1 | Chemie (DBH) | |||
| 4 | F (B) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 5 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | H, I (A, B) | water | water | 18.0 | 134 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 156 (UniProt: P21760)
| PDB | External Database | Details |
|---|---|---|
| Ala 26 | Arg 48 | engineered mutation |
| Val 74 | Leu 96 | SEE REMARK 999 |
| Ala 149 | Glu 171 | engineered mutation |
| Ala 150 | Glu 172 | engineered mutation |
| Leu 157 | - | expression tag |
| Val 158 | - | expression tag |
| Pro 159 | - | expression tag |
| Arg 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36397.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1066.9 | |
| All* | Total formula weight | 37464.5 |
