3SAJ

Crystal Structure of glutamate receptor GluA1 Amino Terminal Domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor 1	polymer	384	44213.2	4	UniProt (P19490) Pfam (PF01094)	Rattus norvegicus (rat)	GluA1, GluR-1, AMPA-selective glutamate receptor 1, GluR-A, GluR-K1, Glutamate receptor ionotropic, AMPA 1
2	E, H, N (E, H, N)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
3	F, G, I, J, K... (F, G, I, J, K...)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	8	In PDB GlyTouCan (G42666HT)
4	M (M)	alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	1	In PDB GlyTouCan (G16404YH)
5	Q, R, S (A, B, D)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
6	T, U, V, W (A, B, C, D)	water	water		18.0	143	Chemie (HOH)

Sequence modifications

A, B, C, D: 4 - 374 (UniProt: P19490)

PDB	External Database	Details
Ile -3	-	expression tag
Glu -2	-	expression tag
Glu -1	-	expression tag
Arg 0	-	expression tag
Gly 1	-	expression tag
Ala 2	-	expression tag
Met 3	-	expression tag
Leu 375	-	expression tag
Glu 376	-	expression tag
Val 377	-	expression tag
Leu 378	-	expression tag
Phe 379	-	expression tag
Gln 380	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	176852.9
Branched	Number of molecules	12
	Total formula weight	6389.9
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	183906.4

*Water molecules are not included.