3S94

Crystal structure of LRP6-E1E2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Low-density lipoprotein receptor-related protein 6	polymer	619	70140.1	2	UniProt (O75581) Pfam (PF00058) Pfam (PF14670)	Homo sapiens (human)	LRP-6
2	C, D (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B: 20 - 630 (UniProt: O75581)

PDB	External Database	Details
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
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His 19	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	140280.1
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	1
	Total formula weight	221.2
All*	Total formula weight	141350.2

*Water molecules are not included.