3S8P

Crystal Structure of the SET Domain of Human Histone-Lysine N-Methyltransferase SUV420H1 In Complex With S-Adenosyl-L-Methionine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Histone-lysine N-methyltransferase SUV420H1	polymer	273	31881.1	2	UniProt (Q4FZB7) Pfam (PF00856)	Homo sapiens (human)	Lysine N-methyltransferase 5B, Suppressor of variegation 4-20 homolog 1, Su(var)4-20 homolog 1, Suv4-20h1
2	C, E (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	D, F (A, B)	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
4	G, H (A, B)	water	water		18.0	270	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	63762.2
Non-Polymers*	Number of molecules	4
	Total formula weight	927.7
All*	Total formula weight	64689.9

*Water molecules are not included.