3S5Y
Pharmacological Chaperoning in Human alpha-Galactosidase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Alpha-galactosidase A | polymer | 398 | 45394.5 | 2 | UniProt (P06280) Pfam (PF16499) Pfam (PF17450) In PDB | Homo sapiens (human) | Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, Melibiase |
| 2 | C | beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)][alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1189.1 | 1 | In PDB GlyTouCan (G26295XE) | |||
| 3 | D | beta-D-xylopyranose-(1-2)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 864.8 | 1 | In PDB GlyTouCan (G06206UV) | |||
| 4 | E | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G11971MR) | |||
| 5 | F | beta-D-xylopyranose-(1-2)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 880.8 | 1 | In PDB GlyTouCan (G71469XA) | |||
| 6 | G | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G18638YB) | |||
| 7 | A, B | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol | non-polymer | 163.2 | 2 | Chemie (DGJ) | |||
| 8 | A, B | NONAETHYLENE GLYCOL | non-polymer | 414.5 | 5 | Chemie (2PE) | |||
| 9 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 10 | B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 11 | B | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 12 | water | water | 18.0 | 440 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 90789.1 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 4237.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2802.2 | |
| All* | Total formula weight | 97829.1 |
