3S4Y
Crystal structure of human thiamin pyrophosphokinase 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Thiamin pyrophosphokinase 1 | polymer | 247 | 27923.8 | 2 | UniProt (Q9H3S4) Pfam (PF04263) Pfam (PF04265) In PDB | Homo sapiens (human) | hTPK1, Placental protein 20, PP20, Thiamine pyrophosphokinase 1 |
2 | A, B | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
4 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
5 | A, B | UNKNOWN ATOM OR ION | non-polymer | 9 | Chemie (UNX) | ||||
6 | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
A, B: 15 - 243 (UniProt: Q9H3S4)
PDB | External Database | Details |
---|---|---|
Met -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
Ser 4 | - | expression tag |
Ser 5 | - | expression tag |
Gly 6 | - | expression tag |
Arg 7 | - | expression tag |
Glu 8 | - | expression tag |
Asn 9 | - | expression tag |
Leu 10 | - | expression tag |
Tyr 11 | - | expression tag |
Phe 12 | - | expression tag |
Gln 13 | - | expression tag |
Gly 14 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 55847.6 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 1411.1 | |
All* | Total formula weight | 57258.7 |