3S3W

Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Amiloride-sensitive cation channel 2, neuronal	polymer	459	52622.8	3	UniProt (Q1XA76) Pfam (PF00858) In PDB	Gallus gallus (bantam chickens)	Acid-sensing ion channel 1
2	D, E, F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
3	A, C	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
4	A, B, C	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
5		water	water		18.0	248	Chemie (HOH)

Sequence modifications

A, B, C: 26 - 463 (UniProt: Q1XA76)

PDB	External Database	Details
Met 5	-	expression tag
Ser 6	-	expression tag
Tyr 7	-	expression tag
Tyr 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
Gly 15	-	expression tag
Ala 16	-	expression tag
Ser 17	-	expression tag
Leu 18	-	expression tag
Val 19	-	expression tag
Pro 20	-	expression tag
Arg 21	-	expression tag
Gly 22	-	expression tag
Ser 23	-	expression tag
His 24	-	expression tag
Met 25	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	157868.5
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	6
	Total formula weight	770.0
All*	Total formula weight	159911.7

*Water molecules are not included.