3S3H

Crystal structure of the catalytic domain of PTP10D from Drosophila melanogaster with a phosphopeptide substrate GP4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Tyrosine-protein phosphatase 10D	polymer	307	35945.6	2	UniProt (P35992) Pfam (PF00102) In PDB	Drosophila melanogaster (Fruit fly)	Receptor-linked protein-tyrosine phosphatase 10D, DPTP10D
2	C	phosphopeptide GP4	polymer	11	1424.5	1
3	A	1-BUTANOL	non-polymer		74.1	1	Chemie (1BO)
4	A	1,4-BUTANEDIOL	non-polymer		90.1	1	Chemie (BU1)
5		water	water		18.0	82	Chemie (HOH)

Sequence modifications

A, B: 24 - 307 (UniProt: P35992)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag
Ala 22	-	expression tag
Ser 23	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	73315.8
Non-Polymers*	Number of molecules	2
	Total formula weight	164.2
All*	Total formula weight	73480.0

*Water molecules are not included.