3S3H

Crystal structure of the catalytic domain of PTP10D from Drosophila melanogaster with a phosphopeptide substrate GP4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0016311	biological_process	dephosphorylation
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0006470	biological_process	protein dephosphorylation
B	0016311	biological_process	dephosphorylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE 1BO A 308

Chain	Residue
A	LEU80

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BU1 A 309

Chain	Residue
B	TYR267

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Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGvgRSG

Chain	Residue	Details
A	VAL240-GLY250

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160, ECO:0000255|PROSITE-ProRule:PRU10044

Chain	Residue	Details
A	CYS242
B	CYS242

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site_id	SWS_FT_FI2
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP210
A	CYS242
A	GLN286
B	ASP210
B	CYS242
B	GLN286

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