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3RZF

Crystal Structure of Inhibitor of kappaB kinase beta (I4122)

Replaces:  3QAD
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MGC80376 proteinpolymer67778001.51UniProt (Q6INT1)
Pfam (PF00069)
Pfam (PF18397)
Xenopus laevis (clawed frog common platanna platanna)
2B
(A)
(4-{[4-(4-chlorophenyl)pyrimidin-2-yl]amino}phenyl)[4-(2-hydroxyethyl)piperazin-1-yl]methanonenon-polymer437.91Chemie (XNM)
Sequence modifications
A: 17 - 675 (UniProt: Q6INT1)
PDBExternal DatabaseDetails
Gln -1-expression tag
Gly 0-expression tag
Gly 1-expression tag
Gly 2-expression tag
Arg 3-expression tag
Ser 4-expression tag
Pro 5-expression tag
Ser 6-expression tag
Leu 7-expression tag
Pro 8-expression tag
Thr 9-expression tag
Gln 10-expression tag
Thr 11-expression tag
Cys 12-expression tag
Gly 13-expression tag
Pro 14-expression tag
Trp 15-expression tag
Glu 16-expression tag
Glu 177Ser 161engineered mutation
Glu 181Ser 165engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight78001.5
Non-Polymers*Number of molecules1
Total formula weight437.9
All*Total formula weight78439.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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