3RZ3
Human Cdc34 E2 in complex with CC0651 inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Ubiquitin-conjugating enzyme E2 R1 | polymer | 183 | 20759.5 | 4 | UniProt (P49427) Pfam (PF00179) | Homo sapiens (human) | Ubiquitin-conjugating enzyme E2-32 kDa complementing, Ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1 |
| 2 | E, F, G, H (A, B, C, D) | 4,5-dideoxy-5-(3',5'-dichlorobiphenyl-4-yl)-4-[(methoxyacetyl)amino]-L-arabinonic acid | non-polymer | 442.3 | 4 | Chemie (U94) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 73 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 7 - 184 (UniProt: P49427)
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | - | expression tag |
| Ala 3 | - | expression tag |
| Met 4 | - | expression tag |
| Gly 5 | - | expression tag |
| Ser 6 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 83038.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1769.2 | |
| All* | Total formula weight | 84807.1 |
