3RYW
Crystal structure of P. vivax geranylgeranyl diphosphate synthase complexed with BPH-811
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Farnesyl pyrophosphate synthase | polymer | 396 | 46215.8 | 4 | UniProt (A5K4U6) Pfam (PF00348) | Plasmodium vivax | |
| 2 | E, J, O, T (A, B, C, D) | {2-[5-(decyloxy)pyridin-3-yl]ethane-1,1-diyl}bis(phosphonic acid) | non-polymer | 423.4 | 4 | Chemie (K9H) | |||
| 3 | F, G, H, K, L... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 4 | I, N, S, X (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | AA, BA, Y, Z (C, D, A, B) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 22 - 396 (UniProt: A5K4U6)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ser 3 | - | expression tag |
| Ser 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ser 12 | - | expression tag |
| Gly 13 | - | expression tag |
| Arg 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Asn 16 | - | expression tag |
| Leu 17 | - | expression tag |
| Tyr 18 | - | expression tag |
| Phe 19 | - | expression tag |
| Gln 20 | - | expression tag |
| Gly 21 | - | expression tag |
| Met 134 | Thr 113 | SEE REMARK 999 |
| Asp 227 | Asn 206 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 184863.0 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2369.4 | |
| All* | Total formula weight | 187232.4 |
