3RYW

Crystal structure of P. vivax geranylgeranyl diphosphate synthase complexed with BPH-811

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Farnesyl pyrophosphate synthase	polymer	396	46215.8	4	UniProt (A5K4U6) Pfam (PF00348) In PDB	Plasmodium vivax
2	A, B, C, D	{2-[5-(decyloxy)pyridin-3-yl]ethane-1,1-diyl}bis(phosphonic acid)	non-polymer		423.4	4	Chemie (K9H)
3	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	12	Chemie (MG)
4	A, B, C, D	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
5		water	water		18.0	71	Chemie (HOH)

Sequence modifications

A, B, C, D: 22 - 396 (UniProt: A5K4U6)

PDB	External Database	Details
Met 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Arg 14	-	expression tag
Glu 15	-	expression tag
Asn 16	-	expression tag
Leu 17	-	expression tag
Tyr 18	-	expression tag
Phe 19	-	expression tag
Gln 20	-	expression tag
Gly 21	-	expression tag
Met 134	Thr 113	SEE REMARK 999
Asp 227	Asn 206	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	184863.0
Non-Polymers*	Number of molecules	20
	Total formula weight	2369.4
All*	Total formula weight	187232.4

*Water molecules are not included.