3RYH
GMPCPP-Tubulin: RB3 Stathmin-like domain complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Tubulin alpha chain | polymer | 451 | 50204.4 | 2 | UniProt (D0VWZ0) | OVIS ARIES (Domestic sheep) | |
| 2 | B, D (B, D) | Tubulin beta chain | polymer | 445 | 50043.9 | 2 | UniProt (D0VWY9) | OVIS ARIES (Domestic sheep) | |
| 3 | E (E) | Stathmin-4 | polymer | 143 | 16746.0 | 1 | UniProt (P63043) Pfam (PF00836) | Rattus norvegicus (rat) | RB3-SLD, Stathmin-like protein B3, RB3 |
| 4 | F, N (A, C) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 2 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 5 | G, L, O, S (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 6 | H, I, J, M, P... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 7 | K, R (B, D) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 2 | Chemie (G2P) | |||
| 8 | V, W, X, Y, Z (A, B, C, D, E) | water | water | 18.0 | 192 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 451 (UniProt: D0VWZ0)
B, D: 1 - 455 (UniProt: D0VWY9)
E: 5 - 145 (UniProt: P63043)
| PDB | External Database | Details |
|---|---|---|
| Ser 232 | Gly 232 | SEE REMARK 999 |
| Ser 340 | Thr 340 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Thr 317 | Ala 315 | SEE REMARK 999 |
| Ile 318 | Val 316 | SEE REMARK 999 |
| Ile 335 | Val 333 | SEE REMARK 999 |
| Ser 375 | Ala 365 | SEE REMARK 999 |
| PDB | External Database | Details |
|---|---|---|
| Ace 3 | - | SEE REMARK 999 |
| Ala 4 | - | SEE REMARK 999 |
| Ala 14 | Cys 58 | engineered mutation |
| Trp 20 | Phe 64 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 217242.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2954.5 | |
| All* | Total formula weight | 220197.1 |
